As U.S. COVID-19 Cases Ease, Questions Remain About Lingering Effects : NPR


A blood circulation dysfunction referred to as Postural Orthostatic Tachycardia Syndrome, often called POTS, is affecting some individuals who proceed to expertise the lingering results of COVID-19.


The easing of the pandemic, a minimum of in the US, provides us somewhat extra head house to consider the aftermath. And a part of the aftermath is bound to be the lingering well being results of COVID. Let’s take into consideration this for a minute. Thirty-three million official COVID instances within the U.S. alone, and a few of these individuals, perhaps thousands and thousands of them, have had signs for greater than a month after their preliminary diseases. For a minimum of a few of these individuals, we will say there’s a analysis and coverings that may assist.

NPR’s Allison Aubrey joins us, as she does most Mondays. Hey there, Allison.

ALLISON AUBREY, BYLINE: Good morning, Steve.

INSKEEP: Let’s begin with the large image. How many individuals are experiencing long-term well being issues right here?

AUBREY: , the estimates actually range. However surveys counsel as much as 10% of individuals have lingering well being issues. Now, there isn’t any clear system for monitoring this, so the numbers simply aren’t concrete. And I might say a part of the frustration, Steve, is that there is such a variety of signs, from fatigue and mind fog and shortness of breath. There simply have not been straightforward solutions. Medical doctors have not been in a position to say when or if individuals will get higher.

This was the state of affairs that Jennifer Minhas was in within the spring of final yr. Let me let you know about her. She’s a 54-year-old nurse. She lives in San Diego. She says her mind fog was so unhealthy that she could not, like, key a four-digit code into her cellphone.

JENNIFER MINHAS: I wasn’t actually in a position to full a full workday. My head simply felt heavy. I could not sit up at my desk. I had, like, profound fatigue. And I may sit there making toast, simply standing up making toast, and my coronary heart fee’s 125.

AUBREY: Now, that is an unusually speedy heartbeat. And it will occur each time she stood up. Her coronary heart would simply race. And this was actually unusual as a result of earlier than COVID, she had been very lively and match. Nevertheless it seems that this was a key symptom, this speedy heartbeat, that finally led medical doctors to diagnose her with a syndrome referred to as POTS.

INSKEEP: Which does not sound too interesting – is that an acronym?

AUBREY: Yeah, it is a mouthful. It stands for postural orthostatic tachycardia syndrome. Now, tachycardia is only a medical time period for a speedy heartbeat. And it is mainly a blood circulation dysfunction. And when you’ve got by no means heard of it, you’re actually not alone. The syndrome predates COVID. It is recognized to return on after viral infections. It is estimated that about one to three million individuals have it. However this is the unusual half. A whole lot of medical doctors do not find out about it as a result of it is solely lately that the syndrome has gained any recognition in any respect.

I spoke to Pam Taub about this. She’s a heart specialist at UC San Diego.

PAM TAUB: POTS occurs – many individuals after a viral an infection. So once I began seeing a few of these COVID long-haulers, I instantly acknowledged that they have been affected by POTS. However, you recognize, POTS has at all times been a situation that is been dismissed as being extra of a psychiatric subject. However that is modified as we have completed extra analysis and have actually proven that there’s actual biology behind POTS.

AUBREY: The speculation of what occurs is that after a virus, the immune system errors antibodies to the virus as one thing dangerous, and so they assault the a part of the nervous system that regulates a complete bunch of capabilities within the physique, together with respiratory, coronary heart fee and blood stress, and that is why all these signs. However the excellent news is that there are therapies that may assist individuals really feel higher.

INSKEEP: Nicely, I wish to ask concerning the therapies. However first, you – we simply heard somebody say that this was dismissed as a psychiatric subject. Why would that be?

AUBREY: Nicely, for causes unknown, the situation impacts much more girls than males. And ladies are inclined to develop autoimmune illnesses extra typically than males typically. Dr. Taub says earlier than the biology of this had begun to be understood, earlier than it was acknowledged {that a} lack of ample blood movement precipitated the mind fog, the signs might be mistaken for, you recognize, stress or anxiousness or the concept it was all in your head.

TAUB: Nicely, sadly, I feel what occurs is – even earlier than COVID, we might seen that our POTS sufferers have been on common having a few one- to two-year delay in analysis. And the reason being their signs are very nonspecific. They’re sometimes younger girls. And you recognize, they begin complaining of issues like mind fog, fatigue. And so they’re normally dismissed.

INSKEEP: Is she’s saying politely that ladies have been simply not taken as critically by medical doctors as perhaps in the event that they have been males?

AUBREY: That is what she’s saying. And there is survey analysis to point out that sometimes girls had an extended time to analysis than males. And POTS sufferers see 5 or extra medical doctors earlier than they’re recognized. And Jennifer Minhas can relate to all of this. Her medical doctors did a lot of coronary heart assessments to ensure her coronary heart was OK. And it was. She had no clots, no coronary heart assault, no arrhythmias. So at first, her medical doctors did not know what to make of her situation.

MINHAS: And so, yeah, my major physician first thought it was anxiousness. That is not my typical persona (laughter). So yeah, it was disconcerning (ph).

INSKEEP: Though it should be a reduction to lastly get a analysis and know that it isn’t all in your head, so to talk. So what therapies has she acquired?

AUBREY: Nicely, the primary therapy is to start out consuming lots of fluids, mainly simply lots of water. It sounds so easy, however this helps to broaden the quantity of plasma. Given the dysfunction within the autonomic nervous system, the physique’s potential to control blood movement is simply broken in individuals with POTS. Train may assist. And Jennifer Minhas says what’s additionally been useful for her is a medicine that is referred to as ivabradine which slows the center fee. She says she seen the consequences straight away.

MINHAS: Inside a pair days, I already began feeling higher. Your physique simply feels such as you’re getting higher blood movement, you recognize? Your mind’s working higher. Your muscle tissues work higher.

AUBREY: And this makes it simpler to train and simply to go about day by day life. So she truly is doing higher. Now, many POTS sufferers require ongoing care. Signs can wax and wane. However she has improved.

INSKEEP: Of these a number of million individuals with lingering results of COVID, what number of have this particular syndrome?

AUBREY: , the prevalence simply will not be recognized. There is no central system to trace this. I imply, the specialists I’ve spoken to, together with at Johns Hopkins and Stanford the place there are POTS specialists, inform me they’ve seen extra sufferers with this post-COVID. Now, there are particular diagnostic assessments. So actually, not everybody with mind fog will probably be recognized with this. And there are various, many different post-viral well being issues which can be unrelated to POTS. The Nationwide Institutes of Well being lately introduced $1.1 billion in analysis funding to higher perceive the myriad causes and potential therapies for all of those individuals with lengthy COVID.

INSKEEP: Allison, if any individual is listening at house and so they have not been recognized with this however they’re pondering, wow, perhaps that is me, what ought to they do?

AUBREY: , I feel it is value bringing this to the eye of your major care physician. There are referral clinics for individuals with dysautonomia. POTS is a type of dysautonomia. And doubtless the very best factor could be for a physician to determine if the signs match sufficient {that a} referral would make sense.

INSKEEP: Allison, thanks for the replace. Actually recognize it.

AUBREY: Thanks, Steve.

INSKEEP: That is NPR’s Allison Aubrey.


Copyright © 2021 NPR. All rights reserved. Go to our web site phrases of use and permissions pages at for additional info.

NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced utilizing a proprietary transcription course of developed with NPR. This textual content is probably not in its ultimate type and could also be up to date or revised sooner or later. Accuracy and availability might range. The authoritative file of NPR’s programming is the audio file.


Please enter your comment!
Please enter your name here